Meanwhile, the doctors spring into action when a couple arrives at the emergency room after escaping a fire. Someone goes to see a priest. Thatcher questions the Chief's recent behavior as Meredith comes to his defense.
- Several weeks after her near-death experience, a recovering Izzie returns to work.
- Simultaneously, we follow the years-long progress of one of Jackson's patients.
- Arizona has a bad day which escalates when she advises one of Callie's patients on a potential double amputation.
- Later, Ryan's mother, Dawn, makes a surprise visit to Newport, and things don't go quite as she and Ryan may have planned due to her constant drinking.
Also Derek treats a patient near and dear to him. Blair feels like her Upper East Side status might be slipping away and devises a plan to assure that doesn't happen. Bailey wishes she didn't have to keep a secret from one of the interns. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr.
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- At the party, Meredith and Derek get caught together by Dr.
- George also begins to overstay his welcome at Burke's apartment after Callie visits him.
- Meredith and George are experiencing morning-after tension at home and at work and it has the rest of the doctors wondering what's up.
- Cristina imagines the two routes her life can take based on one decision she makes.
- Meanwhile, Callie, Arizona and Bailey plan a much needed ladies night for Teddy.
- Derek and Addison's relationship is rocked to the core when a former friend comes to Seattle Grace and his presence promises to shake things up for a few members of the staff.
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She also is reaching the limits of Issie's sunshine and George's politeness as she goes on living with them. Bailey has the idea of opening a free clinic. Kirsten's uptight father, Caleb Nichol, comes for a visit along with his new girlfriend, Gabrielle, a year-old model.
Wyatt refuses to let Meredith give up on therapy. Meanwhile, christian dating sites one of the doctors fights for their life. Burke has a reservation about marrying Cristina.
Meanwhile the hospital is abuzz as Mark attempts a rare face transplant surgery. Meanwhile, dating in bahrain the girls are having fun with their own adventures. Addison gets in trouble after learning that the patient's husband won't use contraceptives. One wrong move puts the lives of Meredith and her baby in jeopardy.
Meanwhile, trouble brews for both Caleb and Kristen at the Newport Group over their legal funds, and Sandy tries to help them out. In this Amelia-centric episode, Amelia engages in the surgery of a lifetime as a crowd of doctors look on from the gallery. Kirsten finds herself surprised by Sandy's new co-worker, online free dating the attractive Rachel.
Having chose Ryan over Luke, Marissa wants to make plans for their first romantic date together, while Ryan does not know how to behave for his first date with Marissa. They work with a woman who is pregnant. Meredith and Cristina lie to each other and themselves about their relationships with McDreamy and Burke, respectively. Meanwhile, Derek gets a phone call that will change his life.
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In this Callie and Arizona centric episode, how the couple takes a look into the problems that have contributed to their troubled marriage. Bailey grows desperate as a patient's condition becomes more and more dire. After a series of deaths at the hospital some of the staff become very superstitious. People are still dealing with the fallout from the ferry disaster.
As the hospital continues to make positive changes under the new management, the doctors begin to realize that owning a hospital comes with its own set of problems and responsibilities. Her friends who she thought had it all, are divorced. Derek and Meredith are fighting over the reason for their sleepless nights. Derek asks Meredith not to ignore him until Addison comes walking around the corner.
Serena loves her new job in Hollywood, but makes a costly misstep when she tries to impress her boss. Meanwhile, Izzie fears the worst when she begins experiencing familiar symptoms. Ryan has a difficult stay in a Juvenile Hall prison for the arson charge.
Serena and Dan pretend to be dating again to protect someone close to them. Meredith and Cristina relate at Emerald City Bar about what dating their respective attendings is like. Cristina, at last awarded her first solo surgery, is more focused on the needs of her friends, and Izzie does her best to keep her medical condition a secret.
If you want to get caught up on everything from the interns first day to the mischief of the last episode, then this is the episode to watch. Izzie and George go crazy trying to get him one. Meredith tries to decide between Derek and Finn and comes to a decision somewhat.
Cristina and Meredith's surgical skills are put to the ultimate test. The rest of the interns operate on a family that was just in a car accident. Burke has a patient who inspires him to talk to Meredith and Cristina about doing what they say they will.
Meanwhile, Callie makes a bold decision regarding her relationship with Arizona, and tragic news brings the doctors together. Recent events strain Burke and Cristina's relationship. George deals with Mac, a friend of the chief, who won't stop flirting with him. This causes tension between Derek and Addison. Things get awkward when the ex-couple's daughter, Michelle, arrives at the hospital.
The Chief officially announces his intention to retire to the administration of Seattle Grace and to Adele. Lily throws Charlie a party to officially introduce her to New York society. Meanwhile, Maggie suspects that Richard knows about her relationship with Andrew, and Arizona debates dating again.